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The Employees' State Insurance Corporation prohibits the purchase, issuance, distribution, and utilization of Coldrif Cough Syrup manufactured by M/s Sresan Pharmaceuticals with immediate effect. All health institutions must withdraw or recall existing stock and return it to the original procurement entity. The Head of the Institution must ensure strict adherence to these instructions. This directive follows child fatalities reported in Madhya Pradesh and Rajasthan.
What you must do
Key dates
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[Image omitted. See the official document.] कर्मचारी राज्य बीमा निगम (श्रम एवं रोजगार मंत्रालय, भारत सरकार) EMPLOYEES' STATE INSURANCE CORPORATION (Ministry of Labour & Employment, Govt. of India)
[Image omitted. See the official document.] मुख्यालय Headquarters' पंचदीप भवन, सी.आई.जी. रोड, नई दिल्ली-110002 PANCHDEEP BHAWAN, C.I.G. MARG, NEW DELHI-110 002 Phone: 011-23604700 Email: dir-gen@esic.nic.in Website : www.esic.nic.in / www.esic.in
U-25/12/Misc./2024-MedV (E-771310)/521 08-10-2025
To
Director (Medical) Delhi / Director (Medical) Noida, Dean, All ESIC PGIMSR's, Medical & Dental Colleges Medical Superintendents - All ESIC Hospitals, Directors, ESI Scheme, All States
Sub: Stop Purchase/Usage/Distribution/Utilisation of Coldrif Cough Syrup-reg.
Ref:
Sir/Madam,
In continuation to ESIC Headquarters Web Upload regarding Advisory on Rational use of Cough Syrups in Paediatric Population dated 08.10.2025, it is informed that incidents of child fatalities have been reported in the States of Madhya Pradesh and Rajasthan following consumption of Coldrif Cough Syrup manufactured by M/s Sresan Pharmaceuticals-Tamil Nadu.
In view of the seriousness of the matter and as a preventive measure, the following directions are hereby issued for strict compliance:
It shall be the sole responsibility of the Head of the Institution to ensure strict adherence to the above instructions.
This is issued for your information and mandatory compliance.
This issues with the approval of the Medical Commissioner (Procurement).
Yours Sincerely
Digitally signed by Sanjiv Kochhar Date: 08-10-2025 Deputy Medical Commissioner (RC)
Copy for information/Coordination to:
[Image omitted. See the official document.] कर्मचारी राज्य बीमा निगम (श्रम एवं रोजगार मंत्रालय, भारत सरकार) EMPLOYEES' STATE INSURANCE CORPORATION (Ministry of Labour & Employment, Govt. of India)
[Image omitted. See. the official document.] मुख्यालय Headquarters' पंचदीप भवन, सी.आई.जी. रोड, नई दिल्ली-110002 PANCHDEEP BHAWAN, C.I.G. MARG, NEW DELHI-110 002 Phone: 011-23604700 Email: dir-gen@esic.nic.in Website : www.esic.nic.in / www.esic.in
U-25/12/Misc./2024-MedV (E-771310)/520 07-10-2025
To,
Director (Medical) Delhi / Director (Medical) Noida, Dean, All ESIC PGIMSR's, Medical & Dental Colleges Medical Superintendents - All ESIC Hospitals, Directors, ESI Scheme, All States
Sub: Advisory on Rational Use of Cough Syrups in Paediatric Population-reg.
Ref: Recent advisory dated 03.10.2025 issued from MoH&FW, GoI for implementation and disseminate information across health institutions.
Sir/Madam,
Reference captioned subject, kind attention is drawn towards the recent advisory dated 03.10.2025 issued by Director General of Health Services, Ministry of Health & Family Welfare, Govt. of India. In this instruction, it has been emphasised to ensure rational drug use and patient safety in paediatric care and reiterating the judicious prescribing and dispensing of cough syrups for children (copy enclosed).
In this context, Head of the respective Institution is hereby directed to:
It is the sole responsibility of the Head of the Institution to implement the above instructions & to ensure prescribing/dispensing of cough and cold medications drugs rationally by Medical Officers etc. under your kind control.
This is for your kind information and mandatory compliance at your end.
This issues with the approval of Medical Commissioner (Procurement).
Yours Sincerely
Encl: As above
Digitally signed by Sanjiv Kochhar Date: 08-10-2025 12:13:16 Deputy Medical Commissioner (RC)
Copy for information/Coordination to:
F. No. 28025/52/2025-SAS.II/EMR Government of India Ministry of Health & Family Welfare Directorate General of Health Services Nirman Bhawan, New Delhi-110011
Dated $3^{\text {rd }}$ October, 2025
To,
The Director Health Services, All States/Union Territories
Sub: Advisory on Rational Use of Cough Syrups in Paediatric Population - reg.
Sir/Madam,
In our continuous efforts to ensure rational drug use and patient safety in paediatric care, this advisory reiterates the judicious prescribing and dispensing of cough syrups for children. Most acute cough illnesses in children are self-limiting and often resolve without pharmacological intervention.
Yours faithfully,
(Dr. Sunita Sharma) DGHS
Copy to:
[unclear in source] 6/10/25
